赵文杰
副教授 硕士生导师
办公室:南校区实验楼A309
邮箱:zhaowenjie@imu.edu.cn
教育背景
2009.09-2011.06:湖南大学 皇冠welcome体育登录入口,研究生/硕士
2012.09-2017.04:湖南大学 皇冠welcome体育登录入口,研究生/博士
工作经历
2011.07-2012.06: 天津凯莱英医药集团 助理研究员
2017.07-2018.07: 山西医科大学 基础医学院 讲师
2018.08-2018.12: 内蒙古大学 皇冠welcome体育登录入口 讲师
2018.12-2021.12: 内蒙古大学 皇冠welcome体育登录入口 副研究员
2022.01--至今: 内蒙古大学 皇冠welcome体育登录入口 副教授
荣誉与奖励
Ø内蒙古自治区第十批“草原英才”入选者(2020年)
Ø内蒙古大学“学术骨干”入选者(2018年)
研究领域
Ø 疾病信号分子响应光学传感器设计;
Ø 生物膜相关细胞生理过程荧光传感研究;
Ø 外泌体蛋白信号转导机理研究。
教学
主讲皇冠welcome体育登录入口 本科生《仪器分析》、《分析化学实验》、《环境化学》、《大学化学》、通识课《化学与现代生活》
研究生《高等分析化学》
研究项目
Ø 国家自然科学基金,单分子力谱成像及定量细胞表面多糖-凝集素相互作用,2024/01-2027/12,主持。
Ø 国家自然科学基金,外泌体中亚磺酸化蛋白识别荧光探针构建及成像应用研究,2020/01-2023/12,主持。
Ø 自治区第十批“草原英才”工程团队和人选奖补资金,2020.01-2021.12,主持,已结题。
Ø 内蒙古自然科学基金,激活式荧光监控双效应介导快速灵敏释放体系构建及其调控活体血糖水平研究,2019/01-2021/12,主持,已结题。
Ø 内蒙古大学2019年引进高层次人才科研启动金,2019/01-2021/01,主持。
代表性成果
学术论文:
(1) Zhirong Li; Lulu Zhang; Zhanzhong Wang; Xiongli Kang; Huiying Jin; Wenjie Zhao*; Jun Zhang*; Haiquan Su; Quantification of Phosphatidylserine Molecules on the Surface of Individual Cells Using Single-Molecule Force Spectroscopy, Analytical Chemistry, 2024, 96:676-684.
(2) Zhirong Li, Jiandong Jia*, Wenjie Zhao*, Leilei Jiang, Wenfei Tian. Seawater as supplemental moisture: The effect of Co-hydrothermal carbonization products obtained from chicken manure and cornstalk. Journal of Environmental Management 2023; 345:118819.
(3) Haofei Zhou, Ye Yuan, Zhexu Wang, Zexin Ren, Mixia Hu, JingKun Lu, Hongxia Gao, Cheng Pan, Wenjie Zhao*, Baohua Zhu*. Co-delivery of doxorubicin and quercetin by Janus hollow silica nanomotors for overcoming multidrug resistance in breast MCF-7/Adr cells. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2023, 658: 130654.
(4) Xiaomei Yang, Zhirong Li, Jun Zhang*, Wenjie Zhao*. Identification of two SPRY isoforms SPRY1 and SPRY3 by atomic force microscopy at the single-molecule level. Analyst, 2022, 147: 5694-5700.
(5) Yanxia Nan, Qiulan Zhou, Wenjie Zhao*, YanbingLu*, Weijian Xu*, In vivo imaging of hypoxia generation stimulated by testosterone using a micelle-based near-infrared fluorescent probe, Sensors & Actuators: B. Chemical, 2019, 288: 543–551.
(6) Yanxia Nan, Wenjie Zhao*, Ningbo Li, Zhiwu Liang, Xinhua Xu*, Chemiluminescence- triggered fluorophore release: Approach for in vivo fluorescence imaging of hydrogen peroxide, Sensors & Actuators: B. Chemical, 2019, 281: 296–302.
(7) Wenjie Zhao, Yinhui Li, Sheng Yang*, Yun Chen, Jing Zheng, Changhui Liu, Zhihe Qing, Jishan Li, and Ronghua Yang*, Target-Activated Modulation of Dual-Color and Two-Photon Fluorescence of Graphene Quantum Dots for in Vivo Imaging of Hydrogen Peroxide, Analytical Chemistry, 2016, 88: 4833-4840.
(8) Wenjie Zhao, Sheng Yang, Jinfeng Yang, Jishan Li, Jing Zheng, Zhihe Qing, and Ronghua Yang*, Visual Biopsy by Hydrogen Peroxide-induced Signal Amplification, Analytical Chemistry, 2016, 88: 10728-10735.
(9) Ningbo Li*, Lingxiao Wang, Haojiang Wang, Jie Qiao, Wenjie Zhao*, XinhuaXu*, Zhiwu Liang, Synthesis and structure of an air-stable bis(pentamethylcyclopentadienyl) zirconium pentafluorbezenesulfonate and its application in catalytic epoxide ring-opening reactions, Tetrahedron, 2018, 74: 1033-1039.
(10) Yanxia Nan, Yu Gu, Qiulan Zhou, Wenjie Zhao *, Jun Zhang*. Ultra-low background signaling cascade amplifiers for in vivo fluorescence imaging of hydroxyl radical production induced by testosterone. New Journal of Chemistry, 2021, 45, 15536.
(11) Yanxia Nan, Yu Gu, Zhen Liu, Qiulan Zhou, Wenjie Zhao*, Weijian Xu*. Versatile quantitative biopsy: an approach for cost-effective detection of hydrogen peroxide in tissue specimens. New Journal of Chemistry., 2021, 45, 4311.
(* Corresponding author)
招生计划
本课题组可招收硕士生及科研助理,欢迎对分析化学及化学生物传感感兴趣的同学咨询联系。个人简历发送至此邮箱:zhaowenjie@imu.edu.cn